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Effect of Femoral Head Size and Surgical Approach on Risk of Revision for Dislocation after Total Hip Arthroplasty

·Acta Orthop·2017·175 citations·Hip & Knee
Free Full Text·DOI·PubMed
SummaryAbstract on PubMed →

This registry study used 166,231 primary THAs from the Dutch Arthroplasty Register to quantify how femoral head size and surgical approach each affect revision risk for dislocation and for all other causes at 6 years. It asks a question that prior studies rarely addressed directly: does reducing dislocation risk through approach selection or head upsizing come at the cost of higher non-dislocation revisions? The answer is approach-dependent and head-size-dependent — and the tradeoffs are clinically meaningful.

Study Snapshot

Design
Retrospective registry cohort
Setting: Nationwide Dutch hospitals, 2007–2015
Funding: None
Objective
Whether femoral head size or surgical approach more strongly reduces dislocation revision risk after THA.
Outcome(s)
Competing-risk cumulative incidence of revision for dislocation and for all other causes at 6 years
Subjects
166,231 non-MoM THAs for primary osteoarthritis
Inclusion
  • Primary osteoarthritis as indication
  • Non-metal-on-metal THA
  • Registered in Dutch Arthroplasty Register 2007–2015
Exclusion
  • AVN, dysplasia, femoral head fracture as indication
  • Metal-on-metal bearing couples
  • First 150 anterior approach cases per hospital (learning curve exclusion)
Follow-up
Median 3.3 years, maximum 9 years
Statistics
Competing-risk analysisMultivariable Cox regressionChi-squared testKaplan-Meier survival

Key Findings

  • Upgrading from 22–28-mm to 32-mm femoral heads reduces dislocation revision risk by ~40% (adjusted HR = 1.6 for smaller heads) across all four approaches, with no increase in non-dislocation revisions. The 32-mm head also achieves the lowest overall all-cause revision rate at 6 years (2.72%) — lower than both smaller and larger heads. This makes 32-mm the safest default choice across approaches.
  • The posterolateral approach carries roughly twice the dislocation revision risk of any other approach: 1.05% vs. 0.5–0.6% crude at 6 years (adjusted HR = 1.0 vs. 0.5–0.6 for all others, p < 0.05). This is the benchmark dislocation risk that head size selection and approach choice are trying to reduce.
  • 36-mm heads reduce dislocation revision risk by a further 40% (adjusted HR = 0.6 vs. 32-mm heads) with the posterolateral approach only — and this benefit is statistically significant. For higher-risk posterolateral patients (male sex, ASA III–IV), upsizing to 36 mm is a reasonable and supported strategy.
  • With the direct anterior approach, 36-mm heads increase non-dislocation revision risk by 50% (adjusted HR = 1.5), driven by aseptic femoral stem loosening. The apparent stability advantage of the anterior approach does not justify upsizing to 36 mm — it makes overall revision outcomes worse.
  • The direct anterior approach has the highest non-dislocation revision rate of any approach (2.9% crude at 6 years) vs. 2.0% for posterolateral (p < 0.05), with the overall all-cause revision rate also highest at 3.5%. This excess persisted after excluding the first 150 cases per hospital at each institution — it is not fully explained by learning curve effects.
  • Male sex, ASA class II or higher, and cementless fixation are each independent risk factors for dislocation revision. Cemented fixation reduces dislocation revision risk by approximately 20% and non-dislocation revision risk by approximately 40% vs. cementless — fixation choice matters beyond just the approach and head size decision.
Board PearlUpgrading to 32-mm femoral heads reduces THA dislocation revision risk by 40% across all approaches; going to 36 mm is safe only with the posterolateral approach.

Clinical Relevance

The central teaching from this paper is that dislocation risk and overall revision risk are not the same target — and optimizing one can worsen the other. For head size, the decision is straightforward: 32-mm heads are a clean win across all approaches, reducing dislocation revision by ~40% with no increase in other revisions. Use 32-mm as your default.

The 36-mm decision is approach-dependent. With the posterolateral approach, 36-mm heads provide additional dislocation protection (HR = 0.6 vs. 32-mm) and are appropriate for higher-risk patients — males and those with ASA III–IV. With the anterior approach, 36-mm heads increase non-dislocation revision risk by 50% and should not be used for this purpose.

The anterior approach's lower dislocation rate comes with a measurable cost: the highest non-dislocation revision rate of any approach (2.9%), predominantly from femoral stem loosening. This persisted after conservative learning curve exclusion (first 150 cases per hospital removed). When counseling patients on anterior approach THA, this tradeoff deserves explicit discussion.

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|

Effect of Femoral Head Size and Surgical Approach on Risk of Revision for Dislocation after Total Hip Arthroplasty

·Acta Orthop·2017·175 citations·Hip & Knee
Free Full Text·DOI·PubMed
SummaryAbstract on PubMed →

This registry study used 166,231 primary THAs from the Dutch Arthroplasty Register to quantify how femoral head size and surgical approach each affect revision risk for dislocation and for all other causes at 6 years. It asks a question that prior studies rarely addressed directly: does reducing dislocation risk through approach selection or head upsizing come at the cost of higher non-dislocation revisions? The answer is approach-dependent and head-size-dependent — and the tradeoffs are clinically meaningful.

Study Snapshot

Design
Retrospective registry cohort
Setting: Nationwide Dutch hospitals, 2007–2015
Funding: None
Objective
Whether femoral head size or surgical approach more strongly reduces dislocation revision risk after THA.
Outcome(s)
Competing-risk cumulative incidence of revision for dislocation and for all other causes at 6 years
Subjects
166,231 non-MoM THAs for primary osteoarthritis
Inclusion
  • Primary osteoarthritis as indication
  • Non-metal-on-metal THA
  • Registered in Dutch Arthroplasty Register 2007–2015
Exclusion
  • AVN, dysplasia, femoral head fracture as indication
  • Metal-on-metal bearing couples
  • First 150 anterior approach cases per hospital (learning curve exclusion)
Follow-up
Median 3.3 years, maximum 9 years
Statistics
Competing-risk analysisMultivariable Cox regressionChi-squared testKaplan-Meier survival

Key Findings

  • Upgrading from 22–28-mm to 32-mm femoral heads reduces dislocation revision risk by ~40% (adjusted HR = 1.6 for smaller heads) across all four approaches, with no increase in non-dislocation revisions. The 32-mm head also achieves the lowest overall all-cause revision rate at 6 years (2.72%) — lower than both smaller and larger heads. This makes 32-mm the safest default choice across approaches.
  • The posterolateral approach carries roughly twice the dislocation revision risk of any other approach: 1.05% vs. 0.5–0.6% crude at 6 years (adjusted HR = 1.0 vs. 0.5–0.6 for all others, p < 0.05). This is the benchmark dislocation risk that head size selection and approach choice are trying to reduce.
  • 36-mm heads reduce dislocation revision risk by a further 40% (adjusted HR = 0.6 vs. 32-mm heads) with the posterolateral approach only — and this benefit is statistically significant. For higher-risk posterolateral patients (male sex, ASA III–IV), upsizing to 36 mm is a reasonable and supported strategy.
  • With the direct anterior approach, 36-mm heads increase non-dislocation revision risk by 50% (adjusted HR = 1.5), driven by aseptic femoral stem loosening. The apparent stability advantage of the anterior approach does not justify upsizing to 36 mm — it makes overall revision outcomes worse.
  • The direct anterior approach has the highest non-dislocation revision rate of any approach (2.9% crude at 6 years) vs. 2.0% for posterolateral (p < 0.05), with the overall all-cause revision rate also highest at 3.5%. This excess persisted after excluding the first 150 cases per hospital at each institution — it is not fully explained by learning curve effects.
  • Male sex, ASA class II or higher, and cementless fixation are each independent risk factors for dislocation revision. Cemented fixation reduces dislocation revision risk by approximately 20% and non-dislocation revision risk by approximately 40% vs. cementless — fixation choice matters beyond just the approach and head size decision.
Board PearlUpgrading to 32-mm femoral heads reduces THA dislocation revision risk by 40% across all approaches; going to 36 mm is safe only with the posterolateral approach.

Clinical Relevance

The central teaching from this paper is that dislocation risk and overall revision risk are not the same target — and optimizing one can worsen the other. For head size, the decision is straightforward: 32-mm heads are a clean win across all approaches, reducing dislocation revision by ~40% with no increase in other revisions. Use 32-mm as your default.

The 36-mm decision is approach-dependent. With the posterolateral approach, 36-mm heads provide additional dislocation protection (HR = 0.6 vs. 32-mm) and are appropriate for higher-risk patients — males and those with ASA III–IV. With the anterior approach, 36-mm heads increase non-dislocation revision risk by 50% and should not be used for this purpose.

The anterior approach's lower dislocation rate comes with a measurable cost: the highest non-dislocation revision rate of any approach (2.9%), predominantly from femoral stem loosening. This persisted after conservative learning curve exclusion (first 150 cases per hospital removed). When counseling patients on anterior approach THA, this tradeoff deserves explicit discussion.

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