This 2017 CDC guideline updates SSI prevention recommendations for all surgical procedures using a GRADE-based systematic review of literature from 1998–2014. It addresses antibiotic prophylaxis timing, skin preparation, glycemic control, normothermia, oxygenation, and antiseptic strategies — with a dedicated section on prosthetic joint arthroplasty.
When planning any clean or clean-contaminated case — including total joint arthroplasty.
Ensure antibiotics are timed for bactericidal tissue levels at incision, stopped at closure regardless of drain presence, blood glucose is below 200 mg/dL intraoperatively, and alcohol-based skin prep is used; these are the highest-evidence levers you control to prevent SSI.
This 2017 CDC guideline updates SSI prevention recommendations for all surgical procedures using a GRADE-based systematic review of literature from 1998–2014. It addresses antibiotic prophylaxis timing, skin preparation, glycemic control, normothermia, oxygenation, and antiseptic strategies — with a dedicated section on prosthetic joint arthroplasty.
When planning any clean or clean-contaminated case — including total joint arthroplasty.
Ensure antibiotics are timed for bactericidal tissue levels at incision, stopped at closure regardless of drain presence, blood glucose is below 200 mg/dL intraoperatively, and alcohol-based skin prep is used; these are the highest-evidence levers you control to prevent SSI.