Fox, Bedi, and Rodeo review the structure, composition, and biomechanical function of articular cartilage. The paper covers its four-zone architecture, ECM constituents, chondrocyte biology, viscoelastic load-bearing mechanisms, age-related changes, and MRI assessment techniques. The central question: what makes cartilage uniquely functional, and why is it so difficult to repair?
Fox, Bedi, and Rodeo review the structure, composition, and biomechanical function of articular cartilage. The paper covers its four-zone architecture, ECM constituents, chondrocyte biology, viscoelastic load-bearing mechanisms, age-related changes, and MRI assessment techniques. The central question: what makes cartilage uniquely functional, and why is it so difficult to repair?