This multi-institutional study of 1,504 revision arthroplasty patients developed a weighted scoring system for diagnosing periprosthetic joint infection. It replaced the expert-opinion-based 2011 MSIS criteria with an evidence-derived, stepwise framework incorporating serum, synovial, and intraoperative markers. The new criteria were externally validated on an independent cohort of 422 patients.
This multi-institutional study of 1,504 revision arthroplasty patients developed a weighted scoring system for diagnosing periprosthetic joint infection. It replaced the expert-opinion-based 2011 MSIS criteria with an evidence-derived, stepwise framework incorporating serum, synovial, and intraoperative markers. The new criteria were externally validated on an independent cohort of 422 patients.