Brittberg tested whether cultured autologous chondrocytes can repair full-thickness cartilage defects of the knee, and whether results differ by defect location. Prospective case series of 23 patients aged 14 to 48 with defects of 1.6 to 6.5 cm2, treated by two-stage chondrocyte transplantation under a periosteal flap, with clinical, arthroscopic and biopsy follow-up for a mean of 39 months.
Brittberg tested whether cultured autologous chondrocytes can repair full-thickness cartilage defects of the knee, and whether results differ by defect location. Prospective case series of 23 patients aged 14 to 48 with defects of 1.6 to 6.5 cm2, treated by two-stage chondrocyte transplantation under a periosteal flap, with clinical, arthroscopic and biopsy follow-up for a mean of 39 months.