To evaluate the association between time to surgery, antibiotic administration, Gustilo grade, fracture location, and development of deep infection in open fractures.
Design: Prospective cohort between 2001 and 2009.
Setting: Three Level 1 Canadian trauma centers.
Participants: A total of 736 (791 fractures) subjects were enrolled and 686 subjects (93%; 737 fractures) provided adequate follow-up data (1-year interview and/or clinical follow-up >90 days).
Intervention:
Main Outcome Measures: Infection requiring unplanned surgical debridement and/or sustained antibiotic therapy.
Infection after open fracture was associated with increasing Gustilo grade or tibia/fibula fractures but not time to surgery or antibiotics.
Level of evidence: Prognostic level I. Copyright remains with the authors and publisher.
To evaluate the association between time to surgery, antibiotic administration, Gustilo grade, fracture location, and development of deep infection in open fractures.
Design: Prospective cohort between 2001 and 2009.
Setting: Three Level 1 Canadian trauma centers.
Participants: A total of 736 (791 fractures) subjects were enrolled and 686 subjects (93%; 737 fractures) provided adequate follow-up data (1-year interview and/or clinical follow-up >90 days).
Intervention:
Main Outcome Measures: Infection requiring unplanned surgical debridement and/or sustained antibiotic therapy.
Infection after open fracture was associated with increasing Gustilo grade or tibia/fibula fractures but not time to surgery or antibiotics.
Level of evidence: Prognostic level I. Copyright remains with the authors and publisher.