No study has attempted to associate the levels of preinjury serum biomarkers of collagen turnover with the subsequent risk of anterior cruciate ligament (ACL) injury.
Hypothesis: Preinjury serum biomarkers of collagen turnover would be associated with the subsequent risk of ACL injury.
Study Design: Case-control study; Level of evidence, 3.
Preinjury differences in serum biomarker levels of collagen turnover suggest that collagen metabolism in individuals who go on to tear an ACL may be different when compared with a matched control group with no history of major joint injury. These differences may be reflective of different preinjury biochemical and/or biomechanical risk profiles or genetic factors that subsequently affect both collagen metabolism and ACL injury risk.
Copyright remains with the authors and publisher.
No study has attempted to associate the levels of preinjury serum biomarkers of collagen turnover with the subsequent risk of anterior cruciate ligament (ACL) injury.
Hypothesis: Preinjury serum biomarkers of collagen turnover would be associated with the subsequent risk of ACL injury.
Study Design: Case-control study; Level of evidence, 3.
Preinjury differences in serum biomarker levels of collagen turnover suggest that collagen metabolism in individuals who go on to tear an ACL may be different when compared with a matched control group with no history of major joint injury. These differences may be reflective of different preinjury biochemical and/or biomechanical risk profiles or genetic factors that subsequently affect both collagen metabolism and ACL injury risk.
Copyright remains with the authors and publisher.