This 2001 current concepts review by Rubin et al. synthesizes animal, in vitro, and clinical data on low-intensity pulsed ultrasound (LIPUS) at 30 mW/cm² for 20 min/day as a noninvasive method to accelerate fracture healing, asking whether biophysical stimulation can meaningfully shorten healing time and reduce nonunion rates across a range of fractures and patient risk factors.
This 2001 current concepts review by Rubin et al. synthesizes animal, in vitro, and clinical data on low-intensity pulsed ultrasound (LIPUS) at 30 mW/cm² for 20 min/day as a noninvasive method to accelerate fracture healing, asking whether biophysical stimulation can meaningfully shorten healing time and reduce nonunion rates across a range of fractures and patient risk factors.