Prospective cohort study of ~900 postmenopausal Japanese-American women followed 4.7 years to determine whether bone mass measurements and existing vertebral fractures independently predict future vertebral fracture risk — and how much risk each factor contributes alone and in combination.
This study provides the quantitative foundation for spine fracture risk stratification - patients with both low bone density and existing vertebral fractures have dramatically elevated risk that should prompt aggressive intervention.
The data supports using bone density measurements combined with careful radiographic assessment for prevalent fractures in postmenopausal women.
Prospective cohort study of ~900 postmenopausal Japanese-American women followed 4.7 years to determine whether bone mass measurements and existing vertebral fractures independently predict future vertebral fracture risk — and how much risk each factor contributes alone and in combination.
This study provides the quantitative foundation for spine fracture risk stratification - patients with both low bone density and existing vertebral fractures have dramatically elevated risk that should prompt aggressive intervention.
The data supports using bone density measurements combined with careful radiographic assessment for prevalent fractures in postmenopausal women.