Patzakis, Clin Orthop Relat Res 1989 - Factors Influencing Infection Rate in Open Fracture Wounds

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Factors Influencing Infection Rate in Open Fracture Wounds

Patzakis, Wilkins·Clin Orthop Relat Res·1989·642 citations·Retrospective cohort

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77 infections in 1104 open fracture wounds were evaluated to identify those factors that predisposed to infection. Factors could be placed into 3 categories: (1) increased risk, (2) no effect, and (3) inconclusive. The single most important factor in reducing the infection rate was the early administration of antibiotics that provide antibacterial activity against both gram-positive and gram-negative microorganisms. In this study, surgical debridement was performed on all open fracture wounds.

Copyright remains with the authors and publisher.

Factors Influencing Infection Rate in Open Fracture Wounds.

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Factors Influencing Infection Rate in Open Fracture Wounds

Patzakis, Wilkins·Clin Orthop Relat Res·1989·642 citations·Retrospective cohort

|

77 infections in 1104 open fracture wounds were evaluated to identify those factors that predisposed to infection. Factors could be placed into 3 categories: (1) increased risk, (2) no effect, and (3) inconclusive. The single most important factor in reducing the infection rate was the early administration of antibiotics that provide antibacterial activity against both gram-positive and gram-negative microorganisms. In this study, surgical debridement was performed on all open fracture wounds.

Copyright remains with the authors and publisher.

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