Retrospective case series of 70 low-energy femoral shaft fractures at a Level 1 trauma center (2002–2007), asking whether long-term alendronate use is associated with a specific fracture pattern: simple transverse fracture with unicortical cortical beaking and diaphyseal cortical hypertrophy.
When you see a low-energy femoral shaft fracture with a simple transverse pattern, cortical beaking, and diaphyseal hypertrophy — especially in a patient on alendronate for more than 4 years — recognize this as a likely bisphosphonate-associated atypical fracture rather than a routine osteoporotic injury, and consider the implications for bone metabolism and healing when planning treatment.
Retrospective case series of 70 low-energy femoral shaft fractures at a Level 1 trauma center (2002–2007), asking whether long-term alendronate use is associated with a specific fracture pattern: simple transverse fracture with unicortical cortical beaking and diaphyseal cortical hypertrophy.
When you see a low-energy femoral shaft fracture with a simple transverse pattern, cortical beaking, and diaphyseal hypertrophy — especially in a patient on alendronate for more than 4 years — recognize this as a likely bisphosphonate-associated atypical fracture rather than a routine osteoporotic injury, and consider the implications for bone metabolism and healing when planning treatment.