This rabbit study tested whether low, physiologic doses of corticosteroid injected directly into normal Achilles tendon weaken it. It correlated tensile failing-strength testing with light and scanning electron microscopy from 48 hours to 6 weeks. The goal was to settle whether steroid harms normal tendon at doses far below the massive doses used in earlier studies.
This rabbit study tested whether low, physiologic doses of corticosteroid injected directly into normal Achilles tendon weaken it. It correlated tensile failing-strength testing with light and scanning electron microscopy from 48 hours to 6 weeks. The goal was to settle whether steroid harms normal tendon at doses far below the massive doses used in earlier studies.