Hsieh, J Bone Joint Surg Am 2004 - Two-Stage Revision Hip Arthroplasty for Infection: Comparison between the Interim Use of Antibiotic-Loaded Cement Beads and a Spacer Prosthesis

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Two-Stage Revision Hip Arthroplasty for Infection: Comparison between the Interim Use of Antibiotic-Loaded Cement Beads and a Spacer Prosthesis

Hsieh, Yang, et al.·J Bone Joint Surg Am·2004·228 citations·Retrospective cohort

Background

A two-stage revision is a well-accepted method for the treatment of a deep infection of a hip with a joint implant. In the present study, the results associated with the interim use of antibiotic-loaded cement beads were compared with those associated with the interim use of an antibiotic-loaded cement prosthesis.

Methods

128 consecutive patients who were managed with a 2-stage revision hip arthroplasty for the treatment of an infection were followed clinically and radiographically for an average of 4.9 years. Cement beads were implanted following resection arthroplasty in the first 70 hips, and a custom cement prosthesis was implanted in the subsequent 58 hips.

Results

There was no evidence of recurrent infection in 122 patients (95.3%); the infection-free rates in both groups were similar.
The use of a spacer prosthesis was associated with a higher hip score, a shorter hospital stay, and better walking capacity in the interim period; a decreased operative time, less blood loss, and a lower transfusion requirement at the time of reimplantation; and fewer postoperative dislocations.

Conclusions

The present study supports the safety and efficacy of the routine use of an antibiotic-loaded cement prosthesis in the interim between the stages of a two-stage revision procedure for the treatment of an infection at the site of a hip arthroplasty.

Copyright remains with the authors and publisher.

Two-Stage Revision Hip Arthroplasty for Infection: Comparison between the Interim Use of Antibiotic-Loaded Cement Beads and a Spacer Prosthesis

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Two-Stage Revision Hip Arthroplasty for Infection: Comparison between the Interim Use of Antibiotic-Loaded Cement Beads and a Spacer Prosthesis

Hsieh, Yang, et al.·J Bone Joint Surg Am·2004·228 citations·Retrospective cohort

Background

A two-stage revision is a well-accepted method for the treatment of a deep infection of a hip with a joint implant. In the present study, the results associated with the interim use of antibiotic-loaded cement beads were compared with those associated with the interim use of an antibiotic-loaded cement prosthesis.

Methods

128 consecutive patients who were managed with a 2-stage revision hip arthroplasty for the treatment of an infection were followed clinically and radiographically for an average of 4.9 years. Cement beads were implanted following resection arthroplasty in the first 70 hips, and a custom cement prosthesis was implanted in the subsequent 58 hips.

Results

There was no evidence of recurrent infection in 122 patients (95.3%); the infection-free rates in both groups were similar.
The use of a spacer prosthesis was associated with a higher hip score, a shorter hospital stay, and better walking capacity in the interim period; a decreased operative time, less blood loss, and a lower transfusion requirement at the time of reimplantation; and fewer postoperative dislocations.

Conclusions

The present study supports the safety and efficacy of the routine use of an antibiotic-loaded cement prosthesis in the interim between the stages of a two-stage revision procedure for the treatment of an infection at the site of a hip arthroplasty.

Copyright remains with the authors and publisher.

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