Enneking, Spanier, and Goodman present the original proposal and multi-institutional validation of a surgical staging system for musculoskeletal sarcomas, addressing the absence of any standardized framework for sarcomas of connective-tissue origin. The paper asks whether a two-variable system — histological grade and compartmentalization — can reliably stratify patients by survival risk and guide surgical margin selection across both bone and soft-tissue sarcomas.
Reference for understanding the Enneking staging system when evaluating sarcoma cases and planning surgical margins.
Enneking, Spanier, and Goodman present the original proposal and multi-institutional validation of a surgical staging system for musculoskeletal sarcomas, addressing the absence of any standardized framework for sarcomas of connective-tissue origin. The paper asks whether a two-variable system — histological grade and compartmentalization — can reliably stratify patients by survival risk and guide surgical margin selection across both bone and soft-tissue sarcomas.
Reference for understanding the Enneking staging system when evaluating sarcoma cases and planning surgical margins.