No article notes available at this time.
• This trial is a key reference in the preoperative-versus-postoperative RT debate for extremity sarcoma — it shows a trend toward more fibrosis with postoperative dosing (66 Gy) but stops short of statistical proof, so residents should recognize this as suggestive rather than definitive evidence. • The finding that fibrosis, stiffness, and edema each independently and significantly reduce functional scores reinforces that late radiation morbidity is not just cosmetic — it has measurable functional consequences that should factor into treatment planning discussions. • The association between field size and toxicity rates underscores the importance of minimizing treatment volume when planning radiotherapy for extremity sarcoma, regardless of sequencing.
No article notes available at this time.
• This trial is a key reference in the preoperative-versus-postoperative RT debate for extremity sarcoma — it shows a trend toward more fibrosis with postoperative dosing (66 Gy) but stops short of statistical proof, so residents should recognize this as suggestive rather than definitive evidence. • The finding that fibrosis, stiffness, and edema each independently and significantly reduce functional scores reinforces that late radiation morbidity is not just cosmetic — it has measurable functional consequences that should factor into treatment planning discussions. • The association between field size and toxicity rates underscores the importance of minimizing treatment volume when planning radiotherapy for extremity sarcoma, regardless of sequencing.