Single-surgeon retrospective cohort study comparing rates of acute deep periprosthetic joint infection (within 90 days) in 2550 consecutive primary hip and knee arthroplasties before versus after implementation of a dilute povidone-iodine wound lavage protocol at closure.
When scrubbing for a primary THA or TKA, advocate for a dilute betadine lavage protocol at your institution: 17.5 mL of 10% povidone-iodine in 500 mL saline soaked for 3 minutes before closure is a $1 intervention with statistically significant infection reduction data behind it.
Be aware this is retrospective evidence — but the safety profile and cost make it a defensible addition to your standard prophylaxis bundle while awaiting RCT confirmation.
Single-surgeon retrospective cohort study comparing rates of acute deep periprosthetic joint infection (within 90 days) in 2550 consecutive primary hip and knee arthroplasties before versus after implementation of a dilute povidone-iodine wound lavage protocol at closure.
When scrubbing for a primary THA or TKA, advocate for a dilute betadine lavage protocol at your institution: 17.5 mL of 10% povidone-iodine in 500 mL saline soaked for 3 minutes before closure is a $1 intervention with statistically significant infection reduction data behind it.
Be aware this is retrospective evidence — but the safety profile and cost make it a defensible addition to your standard prophylaxis bundle while awaiting RCT confirmation.