This matched case-control study (462 cases, 462 controls) from the Mayo Clinic total joint registry used multivariate logistic regression to identify independent risk factors for prosthetic joint infection following THA and TKA between 1969 and 1991.
When evaluating a patient before THA or TKA, check NNIS score, cancer history, and prior surgery on that joint — each independently raises infection risk.
If a postoperative wound problem develops, treat it aggressively: a superficial surgical site infection carries an OR of nearly 36 for subsequent deep prosthetic infection.
This matched case-control study (462 cases, 462 controls) from the Mayo Clinic total joint registry used multivariate logistic regression to identify independent risk factors for prosthetic joint infection following THA and TKA between 1969 and 1991.
When evaluating a patient before THA or TKA, check NNIS score, cancer history, and prior surgery on that joint — each independently raises infection risk.
If a postoperative wound problem develops, treat it aggressively: a superficial surgical site infection carries an OR of nearly 36 for subsequent deep prosthetic infection.