No article notes available at this time.
• This is one of the few randomized trials with two decades of follow-up addressing whether adjuvant radiation after limb-sparing surgery for extremity STS actually improves survival — it does not, at least not to a statistically significant degree. • The very low local recurrence rate in both arms (with a numerical, non-significant edge favoring EBRT) supports radiation's role in local control rather than as a survival-altering intervention, which should shape how residents frame risk-benefit discussions with patients. • Long-term morbidity data (wound complications, edema, functional deficits) help contextualize the trade-offs of adding radiation, since these effects can persist for years after treatment.
No article notes available at this time.
• This is one of the few randomized trials with two decades of follow-up addressing whether adjuvant radiation after limb-sparing surgery for extremity STS actually improves survival — it does not, at least not to a statistically significant degree. • The very low local recurrence rate in both arms (with a numerical, non-significant edge favoring EBRT) supports radiation's role in local control rather than as a survival-altering intervention, which should shape how residents frame risk-benefit discussions with patients. • Long-term morbidity data (wound complications, edema, functional deficits) help contextualize the trade-offs of adding radiation, since these effects can persist for years after treatment.