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A Randomized Controlled Trial of Bone–patellar Tendon–bone Anterior Cruciate Ligament Reconstruction with and without Lateral Extra-Articular Tenodesis: 19-Year Clinical and Radiological Follow-Up

·Am J Sports Med·2020·110 citations·Sports Medicine
DOI·PubMed
SummaryAbstract on PubMed →

This RCT followed 80 knees for a mean of 19.4 years after randomization to BTB ACL reconstruction alone or with a modified Lemaire lateral extra-articular tenodesis (gracilis). It compares long-term patient-reported outcomes, graft survival, and compartment-specific osteoarthritis between the two techniques.

Study Snapshot

Design
Single-center RCT
Setting: Single center, Lyon, France
Objective
Whether BTB ACL reconstruction plus LET improves outcomes and graft survival without increasing OA risk.
Outcome(s)
Subjective IKDC score at mean 19.4-year follow-up
Subjects
121 knees (120 patients); 80 knees at final follow-up
  • 61Isolated BTB ACLR
  • 60BTB ACLR + modified Lemaire gracilis LET
Inclusion
  • Complete isolated primary ACL rupture
  • MRI-confirmed ACL tear
  • Planned arthroscopic ACL reconstruction
Exclusion
  • History of prior ACL repair or reconstruction
  • Associated PCL tear
  • Collateral ligament injury requiring surgery
Follow-up
Mean 19.4 years (range 19-20.2)
Statistics
Fisher exact testStudent t-test / Mann-WhitneyLog-rank survival test

Key Findings

  • Patient-reported outcomes were identical between groups at nearly 20 years. Mean subjective IKDC was 81.8 overall — BTB 81.1 vs BTB-LET 82.4 (P = .7). Lysholm and forgotten knee scores also showed no difference. Two-thirds of patients in both groups were still active in pivoting sports.
  • The graft failure trend favored LET (13% BTB-LET vs 29% BTB, P = .1), but the difference did not reach significance. The authors explicitly state the study was underpowered for this outcome. Only 5 of 17 failed grafts (6%) underwent revision reconstruction.
  • Lateral tibiofemoral OA was significantly more frequent after LET addition (59% vs 22%, P = .02). This finding is confounded by higher perioperative lateral meniscectomy rates in the BTB-LET group (50% vs 17%, P = .03). The OA signal may reflect meniscal loss more than the tenodesis itself.
  • Lateral compartment OA was the only compartment showing a significant difference between the operated and contralateral knee (40% vs 4%, P < .0001). Medial tibiofemoral OA (71% vs 67%) and patellofemoral OA (67% vs 49%) were similarly prevalent in both knees.
  • Unrevised graft failure carried real functional cost: Lysholm 78.5 vs 91.5 (P = .0004) and IKDC 72 vs 84.5 (P = .003) in patients who failed without revision compared to those with intact grafts. Most did not undergo revision because of age at time of failure.
  • Sports participation dropped from 94% preoperatively to 67.5% at final follow-up, with no difference between groups. Only one-third of patients achieved a "forgotten knee" despite mean IKDC scores above 80.
Board PearlLET added to BTB ACL reconstruction improves no functional outcome at 19 years and significantly raises lateral compartment OA risk.

Clinical Relevance

The LET debate comes down to this: does adding a lateral tenodesis protect the graft without harming the joint? Nearly 20 years of RCT data say the functional answer is no — no IKDC benefit, no Lysholm benefit, no return-to-sport benefit.

When counseling a high-risk patient about LET addition (revision setting, high-grade pivot shift, cutting/pivoting athlete), be transparent: the graft-protective trend (13% vs 29% failure) is real but unproven at this sample size. The lateral OA signal (59% vs 22%) is the number that should give you pause, especially if you are also performing a lateral meniscectomy at the same sitting.

The authors' technical note matters clinically: fix the gracilis tenodesis at 30° of flexion in neutral rotation. Not external rotation as classically described. To minimize lateral compartment overconstraint. If you are adding LET and the lateral meniscus needs resection, recognize that combination likely drives the worst OA outcomes in this series.

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|

A Randomized Controlled Trial of Bone–patellar Tendon–bone Anterior Cruciate Ligament Reconstruction with and without Lateral Extra-Articular Tenodesis: 19-Year Clinical and Radiological Follow-Up

·Am J Sports Med·2020·110 citations·Sports Medicine
DOI·PubMed
SummaryAbstract on PubMed →

This RCT followed 80 knees for a mean of 19.4 years after randomization to BTB ACL reconstruction alone or with a modified Lemaire lateral extra-articular tenodesis (gracilis). It compares long-term patient-reported outcomes, graft survival, and compartment-specific osteoarthritis between the two techniques.

Study Snapshot

Design
Single-center RCT
Setting: Single center, Lyon, France
Objective
Whether BTB ACL reconstruction plus LET improves outcomes and graft survival without increasing OA risk.
Outcome(s)
Subjective IKDC score at mean 19.4-year follow-up
Subjects
121 knees (120 patients); 80 knees at final follow-up
  • 61Isolated BTB ACLR
  • 60BTB ACLR + modified Lemaire gracilis LET
Inclusion
  • Complete isolated primary ACL rupture
  • MRI-confirmed ACL tear
  • Planned arthroscopic ACL reconstruction
Exclusion
  • History of prior ACL repair or reconstruction
  • Associated PCL tear
  • Collateral ligament injury requiring surgery
Follow-up
Mean 19.4 years (range 19-20.2)
Statistics
Fisher exact testStudent t-test / Mann-WhitneyLog-rank survival test

Key Findings

  • Patient-reported outcomes were identical between groups at nearly 20 years. Mean subjective IKDC was 81.8 overall — BTB 81.1 vs BTB-LET 82.4 (P = .7). Lysholm and forgotten knee scores also showed no difference. Two-thirds of patients in both groups were still active in pivoting sports.
  • The graft failure trend favored LET (13% BTB-LET vs 29% BTB, P = .1), but the difference did not reach significance. The authors explicitly state the study was underpowered for this outcome. Only 5 of 17 failed grafts (6%) underwent revision reconstruction.
  • Lateral tibiofemoral OA was significantly more frequent after LET addition (59% vs 22%, P = .02). This finding is confounded by higher perioperative lateral meniscectomy rates in the BTB-LET group (50% vs 17%, P = .03). The OA signal may reflect meniscal loss more than the tenodesis itself.
  • Lateral compartment OA was the only compartment showing a significant difference between the operated and contralateral knee (40% vs 4%, P < .0001). Medial tibiofemoral OA (71% vs 67%) and patellofemoral OA (67% vs 49%) were similarly prevalent in both knees.
  • Unrevised graft failure carried real functional cost: Lysholm 78.5 vs 91.5 (P = .0004) and IKDC 72 vs 84.5 (P = .003) in patients who failed without revision compared to those with intact grafts. Most did not undergo revision because of age at time of failure.
  • Sports participation dropped from 94% preoperatively to 67.5% at final follow-up, with no difference between groups. Only one-third of patients achieved a "forgotten knee" despite mean IKDC scores above 80.
Board PearlLET added to BTB ACL reconstruction improves no functional outcome at 19 years and significantly raises lateral compartment OA risk.

Clinical Relevance

The LET debate comes down to this: does adding a lateral tenodesis protect the graft without harming the joint? Nearly 20 years of RCT data say the functional answer is no — no IKDC benefit, no Lysholm benefit, no return-to-sport benefit.

When counseling a high-risk patient about LET addition (revision setting, high-grade pivot shift, cutting/pivoting athlete), be transparent: the graft-protective trend (13% vs 29% failure) is real but unproven at this sample size. The lateral OA signal (59% vs 22%) is the number that should give you pause, especially if you are also performing a lateral meniscectomy at the same sitting.

The authors' technical note matters clinically: fix the gracilis tenodesis at 30° of flexion in neutral rotation. Not external rotation as classically described. To minimize lateral compartment overconstraint. If you are adding LET and the lateral meniscus needs resection, recognize that combination likely drives the worst OA outcomes in this series.

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