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Locking Plate Fixation of Proximal Humerus Fractures in Patients Older Than 60 Years Continues to Be Associated with a High Complication Rate

·J Shoulder Elbow Surg·2020·136 citations·Trauma
DOI·PubMed
SummaryAbstract on PubMed →

Retrospective single-center series of 173 patients over age 60 treated with locking plate ORIF for proximal humerus fractures from 2005 to 2015. Asks whether modern principle-based technique — liberal fibular allograft use, valgus reduction, calcar support — has reduced historically high failure rates in this population. Average follow-up was 6.1 years.

Study Snapshot

Design
Retrospective cohort
Setting: Single center, Mayo Clinic Rochester MN
Funding: None declared
Objective
Whether modern principle-based locking plate ORIF has reduced historically high failure rates in patients >60 with proximal humerus fractures.
Outcome(s)
Radiographic or clinical failure rate at mean 6.1-year follow-up
Subjects
173 patients >60 years (131 with complete follow-up)
Inclusion
  • Age >60 years
  • Proximal humerus fracture treated with locking plate ORIF
  • Treated at Mayo Clinic 2005–2015
Exclusion
  • Nondisplaced or minimally displaced (1-part) fractures
  • Less than 2 years follow-up (unless failure or revision occurred)
Follow-up
Mean 6.1 years (range 2.8 months to 13.3 years)
Statistics
Chi-square testFisher exact testStudent t-test

Key Findings

  • Even with near-perfect technique — 98% valgus or neutral alignment and 95% medial calcar support. Overall failure still reached 34% (44/131 shoulders) and overall complication rate hit 44%. Optimizing hardware placement does not overcome the biological vulnerability of the elderly proximal humerus.
  • Failure scaled with fracture complexity, though none of the differences reached statistical significance:
    –2-part: 26% failure
    –3-part: 39% failure
    –4-part: 45% failure
    –This gradient is clinically coherent and drives the shift toward primary rTSA for complex fractures.
  • The dominant failure mode was biological, not mechanical. AVN with severe head collapse drove 52% of all failures. More than half of failures appeared after 6 months. Fracture union on X-ray does not mean the head is safe.
  • Failure trended sharply with age:
    –60s: 26%
    –70s: 40%
    –80s: 48% (P>0.5)
    –The gradient did not reach significance, but the clinical pattern is consistent and should factor into shared decision-making with older patients.
  • Fibular allograft augmentation provided no measurable benefit: failure was 33% with allograft vs. 34% without (P>0.99). This argues against augmentation as a biological rescue strategy in high-risk patients.
  • A reoperation rate of only 11% (14 patients) does not reflect good outcomes. Most failures were managed nonoperatively. Not because patients were functioning well, but because elderly patients often decline further surgery despite ongoing pain and dysfunction.
  • Functional outcomes in the failure group were significantly worse: SANE score 77 vs. 92 (P<0.0001) and VAS with activity 2.4 vs. 1.0 (P=0.003). Radiographic failure translates directly into measurable patient-reported impairment.
Board PearlLocking plate ORIF for proximal humerus fractures in patients >60 yields a 34% failure rate even with optimal technique — AVN drives most failures, not fixation error.

Clinical Relevance

A 73-year-old woman with a displaced 3-part proximal humerus fracture sits across from you in clinic. The question is not whether you can fix it — you almost certainly can, with valgus reduction and calcar support 95-98% of the time. The question is whether fixation will hold.

This paper makes the answer uncomfortable: even at a high-volume center after the learning curve, 39% of 3-part and 45% of 4-part fractures fail in patients over 60. Most failures are biological. Progressive AVN that unfolds months after the plate has done its job. No amount of technique refinement prevents a head with compromised vascularity from collapsing.

When you see a displaced 3- or 4-part fracture in a patient in their 70s or 80s, these data support a direct conversation about primary rTSA. The authors' own practice shifted in that direction, citing an approximately 5% failure rate for rTSA in this setting versus 39-45% for ORIF.

Do not let a low reoperation rate (11%) reassure you. Most failures in this series went unrevised because patients refused further surgery, not because they recovered.

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|

Locking Plate Fixation of Proximal Humerus Fractures in Patients Older Than 60 Years Continues to Be Associated with a High Complication Rate

·J Shoulder Elbow Surg·2020·136 citations·Trauma
DOI·PubMed
SummaryAbstract on PubMed →

Retrospective single-center series of 173 patients over age 60 treated with locking plate ORIF for proximal humerus fractures from 2005 to 2015. Asks whether modern principle-based technique — liberal fibular allograft use, valgus reduction, calcar support — has reduced historically high failure rates in this population. Average follow-up was 6.1 years.

Study Snapshot

Design
Retrospective cohort
Setting: Single center, Mayo Clinic Rochester MN
Funding: None declared
Objective
Whether modern principle-based locking plate ORIF has reduced historically high failure rates in patients >60 with proximal humerus fractures.
Outcome(s)
Radiographic or clinical failure rate at mean 6.1-year follow-up
Subjects
173 patients >60 years (131 with complete follow-up)
Inclusion
  • Age >60 years
  • Proximal humerus fracture treated with locking plate ORIF
  • Treated at Mayo Clinic 2005–2015
Exclusion
  • Nondisplaced or minimally displaced (1-part) fractures
  • Less than 2 years follow-up (unless failure or revision occurred)
Follow-up
Mean 6.1 years (range 2.8 months to 13.3 years)
Statistics
Chi-square testFisher exact testStudent t-test

Key Findings

  • Even with near-perfect technique — 98% valgus or neutral alignment and 95% medial calcar support. Overall failure still reached 34% (44/131 shoulders) and overall complication rate hit 44%. Optimizing hardware placement does not overcome the biological vulnerability of the elderly proximal humerus.
  • Failure scaled with fracture complexity, though none of the differences reached statistical significance:
    –2-part: 26% failure
    –3-part: 39% failure
    –4-part: 45% failure
    –This gradient is clinically coherent and drives the shift toward primary rTSA for complex fractures.
  • The dominant failure mode was biological, not mechanical. AVN with severe head collapse drove 52% of all failures. More than half of failures appeared after 6 months. Fracture union on X-ray does not mean the head is safe.
  • Failure trended sharply with age:
    –60s: 26%
    –70s: 40%
    –80s: 48% (P>0.5)
    –The gradient did not reach significance, but the clinical pattern is consistent and should factor into shared decision-making with older patients.
  • Fibular allograft augmentation provided no measurable benefit: failure was 33% with allograft vs. 34% without (P>0.99). This argues against augmentation as a biological rescue strategy in high-risk patients.
  • A reoperation rate of only 11% (14 patients) does not reflect good outcomes. Most failures were managed nonoperatively. Not because patients were functioning well, but because elderly patients often decline further surgery despite ongoing pain and dysfunction.
  • Functional outcomes in the failure group were significantly worse: SANE score 77 vs. 92 (P<0.0001) and VAS with activity 2.4 vs. 1.0 (P=0.003). Radiographic failure translates directly into measurable patient-reported impairment.
Board PearlLocking plate ORIF for proximal humerus fractures in patients >60 yields a 34% failure rate even with optimal technique — AVN drives most failures, not fixation error.

Clinical Relevance

A 73-year-old woman with a displaced 3-part proximal humerus fracture sits across from you in clinic. The question is not whether you can fix it — you almost certainly can, with valgus reduction and calcar support 95-98% of the time. The question is whether fixation will hold.

This paper makes the answer uncomfortable: even at a high-volume center after the learning curve, 39% of 3-part and 45% of 4-part fractures fail in patients over 60. Most failures are biological. Progressive AVN that unfolds months after the plate has done its job. No amount of technique refinement prevents a head with compromised vascularity from collapsing.

When you see a displaced 3- or 4-part fracture in a patient in their 70s or 80s, these data support a direct conversation about primary rTSA. The authors' own practice shifted in that direction, citing an approximately 5% failure rate for rTSA in this setting versus 39-45% for ORIF.

Do not let a low reoperation rate (11%) reassure you. Most failures in this series went unrevised because patients refused further surgery, not because they recovered.

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